Toxic Pustuloderma associated with clemastine therapy

Toxic epidermal necrolysis associated with deflazacort therapy with nephrotic syndrome

Toxic epidermal necrolysis (TEN) is a drug-related fatal disease. Extensive necrosis of the epidermis can lead to serious complications. This report describes two cases of TEN, associated with deflazacort (DFZ), in two boys, aged 4 years and 14 years, with nephrotic syndrome (NS). The 14-year-old male teenager received DFZ following NS relapse. After 17 days, pruritic papules appeared on the lo...

Arthritis Associated With Low Dose Methimazole Therapy: A Case Report.

Here in this paper, we report a 31-year-old case admitted with symptoms of hyperthyroidism that was then diagnosed with Grave's disease (GD) and underwent treatments with a low dosage of methimazole (10 mg/day). 20 days after treatments initiations, she developed antithyroid arthritis syndrome. This patient experienced arthritis and arthralgia in at least 4 joints. And all autoimmune and microb...

Toxic Symptoms Associated with Quinacrine Treatment

Toxic symptoms such as restlessness, staring at others, incoherent talks, shouting all day and night, etc., were observed in 16 cases of malaria patients out of 450 treated with quinacrine. The average dose in all the cases did not exceed 2.8 gm. in one course of treatment. Majority of the cases referred above developed symptoms on the 3rd to 4th day of quinacrine administration. The setiologic...

Toxic epidermal necrolysis associated with streptococcal septicaemia.

Toxic Epidermal Necrolysis Associated with Antiepileptic Drugs and Cranial Radiation Therapy

Case reports on the development of toxic epidermal necrolysis (TEN) associated with concurrent administration of phenytoin with cranial radiation therapy (Ahmed (2004), Criton et al. (1997), and Rzany et al. (1996)), but reports about erythema multiforme, which can develop in patients treated with levetiracetam and cranial irradiation, are very limited. This paper presents evidence that TEN may...